Fusobacterium in Colonic Flora and Molecular Features of Colorectal Carcinoma
نویسندگان
چکیده
منابع مشابه
Fusobacterium in colonic flora and molecular features of colorectal carcinoma.
Fusobacterium species are part of the gut microbiome in humans. Recent studies have identified overrepresentation of Fusobacterium in colorectal cancer tissues, but it is not yet clear whether this is pathogenic or simply an epiphenomenon. In this study, we evaluated the relationship between Fusobacterium status and molecular features in colorectal cancers through quantitative real-time PCR in ...
متن کاملClinical Studies Fusobacterium in Colonic Flora and Molecular Features of Colorectal Carcinoma
Fusobacterium species are part of the gut microbiome in humans. Recent studies have identified overrepresentation of Fusobacterium in colorectal cancer tissues, but it is not yet clear whether this is pathogenic or simply an epiphenomenon. In this study, we evaluated the relationship between Fusobacterium status and molecular features in colorectal cancers through quantitative real-time PCR in ...
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Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma Mauro Castellarin, René L. Warren, J. Douglas Freeman, Lisa Dreolini, Martin Krzywinski, Jaclyn Strauss, Rebecca Barnes, Peter Watson, Emma Allen-Vercoe, Richard A. Moore, and Robert A. Holt BC Cancer Agency, Michael Smith Genome Sciences Centre, Vancouver, British Columbia V5Z 1L3, Canada; Department of Molecular Biol...
متن کاملFusobacterium nucleatum in Colorectal Carcinoma Tissue According to Tumor Location
OBJECTIVES Evidence suggests a possible role of Fusobacterium nucleatum in colorectal carcinogenesis, especially in right-sided proximal colorectum. Considering a change in bowel contents and microbiome from proximal to distal colorectal segments, we hypothesized that the proportion of colorectal carcinoma enriched with F. nucleatum might gradually increase along the bowel subsites from rectum ...
متن کاملGenomic analysis identifies association of Fusobacterium with colorectal carcinoma.
The tumor microenvironment of colorectal carcinoma is a complex community of genomically altered cancer cells, nonneoplastic cells, and a diverse collection of microorganisms. Each of these components may contribute to carcinogenesis; however, the role of the microbiota is the least well understood. We have characterized the composition of the microbiota in colorectal carcinoma using whole geno...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2014
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-13-1865